Blue Dextrans

Blue Dextrans

CAS Number: 87915-38-6

Blue dextrans are synthesised from controlled dextran fractions by reacting with Cibacron blue F3GA. After purification from non-bound dye, products are controlled for molecular weight, solubility, degree of substitution, free dye and loss on drying. TdB Labs offer blue dextran in a wide variety of molecular weights, ranging from 5 kDa to 2000 kDa.

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Structure
Dextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F; and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of side chains linked to 3-carbon of glucose. The dextran is then labelled with Cibacron blue F3GA.

Storage and stability
Blue dextrans are stable for more than 6 years when stored dry in well-sealed containers at ambient temperature

Solubility
Blue dextran dissolves freely in water.

Applications
Blue dextran has long been used as a void volume marker in chromatography. Blue dextran can also be used as a molecular marker. Read more about application here.

References

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  1. Beugeling, M. et al. The mechanism behind the biphasic pulsatile drug release from physically mixed poly(dl-lactic(-co-glycolic) acid)-based compacts. International Journal of Pharmaceutics 551, 195–202 (2018).
  2. Russo, D. et al. Direct photolysis of benzoylecgonine under UV irradiation at 254nm in a continuous flow microcapillary array photoreactor. Chemical Engineering Journal 283, 243–250 (2016).
  3. Vagenende, V., Ching, T.-J., Chua, R.-J., Jiang, Q. Z. & Gagnon, P. Self-assembly of lipopolysaccharide layers on allantoin crystals. Colloids and Surfaces B: Biointerfaces 120, 8–14 (2014).

How to order

Visit our webshop to see the molecular weights and pack sizes available. Please send an e-mail to order@tdblabs.se if you would like to receive a quote, place a bulk order or if you wish to place your order manually.

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