Blue dextrans are synthesised from controlled dextran fractions by reacting with Cibacron blue F3GA. After purification from non-bound dye, products are controlled for molecular weight, solubility, degree of substitution, free dye and loss on drying. TdB Labs offer blue dextran in a wide variety of molecular weights, ranging from 5 kDa to 2000 kDa.
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Dextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F; and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of side chains linked to 3-carbon of glucose. The dextran is then labelled with Cibacron blue F3GA.
Storage and stability
Blue dextrans are stable for more than 6 years when stored dry in well-sealed containers at ambient temperature
Blue dextran dissolves freely in water.
Blue dextran has long been used as a void volume marker in chromatography. Blue dextran can also be used as a molecular marker. Read more about application here.
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Beugeling, M. et al. The mechanism behind the biphasic pulsatile drug release from physically mixed poly(dl-lactic(-co-glycolic) acid)-based compacts. International Journal of Pharmaceutics551, 195–202 (2018).
Russo, D. et al. Direct photolysis of benzoylecgonine under UV irradiation at 254nm in a continuous flow microcapillary array photoreactor. Chemical Engineering Journal283, 243–250 (2016).
Vagenende, V., Ching, T.-J., Chua, R.-J., Jiang, Q. Z. & Gagnon, P. Self-assembly of lipopolysaccharide layers on allantoin crystals. Colloids and Surfaces B: Biointerfaces120, 8–14 (2014).
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