Journal of Chromatography has recently published a new study on IgG purification optimisation. The study employs protein A agarose beads for purification of the antibodies and focuses on changes in pore and filament diameters due to adsorption.
The authors have used flourescein isothiocyanate-dextran (FITC-dextran) of 2000 kDa from TdB Labs in their study and report a dramatic pore diameter reduction, suggesting a geometrical model to predict IgG diffusion.
Full article here.
Read more about FITC dextran here.
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