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FITC (Fluorescein isothiocyanate), introduced in 1942, is essential in biochemical research for labeling proteins and antibodies. Its reactive isothiocyanate group forms stable bonds with primary amines, enabling the creation of highly fluorescent derivatives. This has revolutionized staining techniques, though optimal labeling varies with molecular weight to avoid issues like quenching or nonspecific binding.

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Dextran sulfate, a sulfated polysaccharide derived from dextran, has significant applications in hematology due to its anticoagulant properties. Hematology focuses on blood and blood-related disorders, as well as the study of blood-forming organs and tissues like bone marrow, lymph nodes, and spleen.

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In a recent study on regenerative medicine published in the Biomaterial Journal, researchers shared their latest results on dental pulp stem cells and their anti-oxidative properties in the context of tissue engineering where they utilized TdB Labs AB Labs pH meter to monitor pH levels. They discovered that incorporating dental pulp stem cell-conditioned medium (DPSC-CM) significantly reduced oxidative stress, enhancing cell viability and biocompatibility.

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Fluorescein isothiocyanate (FITC) is a vital component in the world of biochemistry and molecular biology. At TdB Labs, we pride ourselves on offering high-quality FITC, both as a stand-alone dye and conjugated to dextran and other polysaccharides. In this article, we delve into the unique properties and applications of FITC, highlighting why it is one of our most important products.

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The blood-brain barrier (BBB) is a highly selective, semipermeable border that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS). Composed of endothelial cells with tight junctions, astrocyte end-feet, and pericytes, the BBB plays a crucial role in maintaining the brain’s microenvironment. It restricts the passage of pathogens, toxins, and large or hydrophilic molecules while allowing essential nutrients and gases to pass through.

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Diagnosing acute pancreatitis remains challenging due to high error rates in standard clinical panels. This complexity is heightened by macroamylasemia which is characterized by the presence of elevated levels of macroamylase in the blood and can lead to falsely elevated amylase results unless specifically ruled out. This article discusses the general challenges in diagnosing pancreatitis and specifically highlights how the gel permeation chromatography (GPC) method using Blue Dextran 2000 (BD2000) can be used to rule out pancreatitis by accurately measuring macroamylase levels.

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TdB Labs stands at the forefront, offering an exceptional range of Blue Dextran products, renowned for their quality and adaptability across a spectrum of molecular weights, from 5 kDa to 2000 kDa…

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