White Paper

Blue dextran has long been a staple in biochemical and analytical workflows, but its capabilities extend far beyond its traditional role. While lower molecular weight variants (e.g., BD70, BD500) are useful for diffusion and permeability studies, high molecular weight variants (e.g., BD2000) remains the most widely used due to its robustness and reproducibility across biochemical and biophysical research involving chromatography studies, affinity interactions, permeability and barrier integrity testing, drug delivery and molecular biology.

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31/03/2026

Dextran sulfate is a highly effective additive for mitigating aggregation in CHO-based mAb production, leading to improved cell viability, reduced apoptosis, and enhanced productivity without negatively affecting antibody quality (e.g. glycosylation, aggregation, charge).

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31/03/2026

DSS40 (Dextran Sulfate Sodium) is a pivotal reagent in colitis research, used to induce colitis in experimental models and to study the gut microbiome. This facilitates the study of inflammatory bowel disease mechanisms and the development of potential treatments.

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23/04/2025

Early diagnosis of tuberculosis (TB) is crucial for effective treatment and prevention of transmission. However, TB diagnostics face significant challenges, including the complexity of detecting Mycobacterium tuberculosis in diverse environments and the need for highly specific and sensitive diagnostic tools. FITC-Trehalose is a promising candidate for in vivo and in vitro diagnostics

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10/3/2025

IBD, including Crohn’s disease and ulcerative colitis, results from a dysregulated immune response in the gastrointestinal tract. Despite extensive research, the exact cause remains elusive, involving genetic and environmental factors. Understanding the mechanisms behind this inflammatory response is crucial for developing effective treatments.

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28/1/2025

The blood-brain barrier (BBB) is a vital biological interface that preserves brain homeostasis by controlling the entry of substances, ions, and xenobiotics into the brain’s extracellular space. As you can read in this white paper, researchers study the permeability of the BBB using FITC- and TRITC-dextran with different molecular weights.

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7/1/2025

Inulin is a naturally occurring polysaccharide found in many plants, primarily used as a dietary fiber. It has significant applications in the pharmaceutical and medical industries due to its prebiotic properties, which promote gut health, and its potential in drug delivery systems.

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18/12/2024