
Chromatography
Blue dextran is used in affinity chromatography allowing for the identification of proteins, (purified or in crude cellular extracts), and improving the purification procedures for various proteins (1). Bearing Cibacron Blue F3G-A, blue dextran was very early found to bind to pyruvate kinase1, and this observation enabled the purification of a whole series of proteins and essentially brought the use of textile dyes in protein purification to the fore (2). Blue dextrans are also utilized in gel filtration and protein chromatography, and molecular weight markers.