Blue dextran

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Blue dextran

CAS Number: 87915-38-6

Blue dextran is synthesized from controlled dextran fractions by reacting with Cibacron blue F3GA. After purification from non-bound dye, products are controlled for molecular weight, solubility, degree of substitution, free dye and loss on drying. TdB Labs offer blue dextran in a wide variety of molecular weights, ranging from 5 kDa to 2000 kDa.

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Blue dextran

Structure
Dextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F; and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of side chains linked to 3-carbon of glucose. The dextran is then labelled with Cibacron blue F3GA.
Storage and stability
Blue dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.
Solubility
Blue dextran dissolves freely in water.
Applications
Blue dextran has long been used as a void volume marker in chromatography. Blue dextran can also be used as a molecular marker. Read more about application here.

References

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  1. Pérez-Martín, E. et al. Refining Stereotaxic Neurosurgery Techniques and Welfare Assessment for Long-Term Intracerebroventricular Device Implantation in Rodents. Animals 13, 2627–2627 (2023).
  2. Reinhold, A.-K., Salvador, E., Förster, C. Y., Birklein, F. & Rittner, H. L. Microvascular Barrier Protection by microRNA-183 via FoxO1 Repression: A Pathway Disturbed in Neuropathy and Complex Regional Pain Syndrome. The Journal of Pain 23, 967–980 (2022).
  3. Beugeling, M. et al. The mechanism behind the biphasic pulsatile drug release from physically mixed poly(dl-lactic(-co-glycolic) acid)-based compacts. International Journal of Pharmaceutics 551, 195–202 (2018).
  4. Russo, D. et al. Direct photolysis of benzoylecgonine under UV irradiation at 254nm in a continuous flow microcapillary array photoreactor. Chemical Engineering Journal 283, 243–250 (2016).
  5. Vagenende, V., Ching, T.-J., Chua, R.-J., Jiang, Q. Z. & Gagnon, P. Self-assembly of lipopolysaccharide layers on allantoin crystals. Colloids and Surfaces B: Biointerfaces 120, 8–14 (2014).

Technical documents

Specifications

How to order

Visit our webshop to see the molecular weights and pack sizes available. Please send an e-mail to order@tdblabs.se if you would like to receive a quote, place a bulk order or if you wish to place your order manually.

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