Apart from dextran derivatives, TdB Labs also produce derivatives of other polysaccharides such as polysucrose, inulin, hyaluronic acid, trehalose and hydroxyethyl starch. Our product portfolio includes charged polysaccharides with functional groups like carboxymethyl (CM), diethylaminoethyl (DEAE) and quaternary-ammonium (Q).
Polysaccharide derivatives have multiple usage areas. For example, they can be sued for coating of medical devices, as stabilisers for proteins and hydrogels, as adjuvants in vaccines and more.
CAS Number: 39422-83-8
CM-dextran consists of a dextran backbone substituted with anionic carboxymethyl substituents. TdB Labs produce CM-dextrans from 4 kDa to 150 kDa.
DEAE-Polysucrose is a polysucrose substituted with cationic diethylaminoethyl (DEAE) groups. The DEAE-polysucrose from TdB Labs is derived from a polysucrose with an average molecular weight of approximately 70 kDa.
Phenyl-dextrans are synthesised from selected controlled dextran fractions by reacting with an appropriate epoxide. TdB labs produce phenyl-dextran with a mean molecular weight of 5 kDa, 40 kDa and 150 kDa.
Polysucrose molecules are highly branched, and the high content of hydroxyl groups leads to very good solubility in aqueous media. Polysucroses behave as an ideal neutral sphere and displays excellent biocompatibility. TdB Labs produce polysucrose from 20 kDa to 1000 kDa.
Hyaluronic acid is a polysaccharide composed of alternating β(1-3) glucuronide and β(1-4) glucosaminide units derived from rooster combs or Streptococcus equi. TdB Labs supply derivatives of either of these qualities labelled with fluorescein (F-HA) or tetramethylrhodamine (T-HA).