We follow with excitement how dextran derivatives are today successfully used in lung and cell imaging for studying respiratory viral infections including coronavirus. One recent example published in Nature is an in vivo two-photon imaging study looking at transformations of lung during an influenza virus infection (Ueki et al, Nature Protocols 2020). Another example is a study of human coronavirus entry to the cell elegantly performed using fluorescent confocal microscopy (Owczarek et at, Nature Scientific Reports 2018).
If you want to learn more about how dextran can be used in your research on coronavirus, SARS or other pathogens and cellular pathways, contact us for a free consultation to assist you in finding a faster and simpler way to accelerate your research and make your experiments more successful.
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References:
Owczarek, K., Szczepanski, A., Milewska, A. et al. Early events during human coronavirus OC43 entry to the cell. Sci Rep 8, 7124 (2018). https://doi.org/10.1038/s41598-018-25640-0.
Ueki, H., Wang, I., Zhao, D. et al. Multicolor two-photon imaging of in vivo cellular pathophysiology upon influenza virus infection using the two-photon IMPRESS. Nat Protoc 15, 1041–1065 (2020). https://doi.org/10.1038/s41596-019-0275-y
