CM-dextran consists of a dextran backbone substituted with carboxymethyl substituents imparting a polyanionic character to the product. All batches are checked for molecular weight, degree of substitution and loss on drying. TdB labs produce CM-dextrans from 4 kDa to 150 kDa. CM-dextran is supplied as a white powder.
Can’t find what you are looking for? We can always produce a customised product for you. Read more here.
If you need larger quantities, please contact us for a bulk quotation.
Structure Polysucrose is a high molecular weight sucrose-polymer formed by copolymerisation of sucrose with epichlorohydrin. The molecules are highly branched, and the high content of hydroxyl groups leads to very good solubility in aqueous media. In CM-polysucrose, the carboxyl content is approximately 5% which is equivalent to about one CM-group for every five glucose and fructose units.
Storage and stability
CM-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.
Solubility CM-dextran dissolves readily in water.
CM-dextran can be used as stabilisers for sensitive biopolymers, as non-toxic ingredients in formulations, as reagents for binding cations (inorganic and organic) via carboxyl reactions and more. Read more about application here.
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Juenet, M. et al. Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin. Biomaterials156, 204–216 (2018).
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