CM-dextran consists of a dextran backbone substituted with carboxymethyl substituents imparting a polyanionic character to the product. All batches are checked for molecular weight, degree of substitution and loss on drying. TdB Labs produce CM-dextrans from 4 kDa to 150 kDa. CM-dextran is supplied as a white powder.
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Structure CM-dextrans are manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali. This leads to the introduction of O-carboxymethyl groups along the dextran chain. The carboxyl content is approximately 5% which is equivalent to about one CM group for every 5 five glucose units. Higher degrees of substitution may be achieved if required.
Storage and stability
CM-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.
Solubility CM-dextran dissolves readily in water.
CM-dextran can be used as stabilisers for sensitive biopolymers, as non-toxic ingredients in formulations, as reagents for binding cations (inorganic and organic) via carboxyl reactions and more. Read more about application here.
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