Q-dextran is a polycationic derivative of dextran. These derivatives are distinct from DEAE-dextrans in that they only contain quaternary amine groups. Unlike DEAE-dextrans, Q-dextrans will be charged over a wide range of pH (pH 4-10). Q-dextrans will also have a much stronger net charge than corresponding DEAE-dextrans. All batches are checked for molecular weight, degree of substitution and loss on drying. TdB Labs produce Q-dextran from 4 kDa to 150 kDa. Q-dextrans are supplied as a white powder.
Can’t find what you are looking for? We can always produce a customised product for you. Read more here.
Structure Q-dextrans are synthesised by reacting dextran fractions with 2,3-epoxypropyltrimethylammonium chloride. The nitrogen content is approximately 2% which corresponds to one quaternary ammonium group for every four glucose units.
Storage and stability
Q-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.
Solubility Q-dextran dissolves readily in water.
Polycationic products exhibit a wide variety of effects in cellular systems and are of interest as adjuvants in vaccines. Q-dextran has a much stronger net charge than corresponding DEAE-dextrans and will thus give enhanced responses in systems where this effect is important. Read more about application here.
Have you cited this product in a publication? Let us know so we can reference it.
Visit our webshop to see the molecular weights and pack sizes available. Please send an e-mail to firstname.lastname@example.org if you would like to receive a quote, place a bulk order or if you wish to place your order manually.
In need of an expert on dextran derivatives?
Let TdB Labs’ products and services help you achieve your research goals.