Polysucroses (renamed from Ficoll™) are formed by copolymerization of sucrose with epichlorohydrin. The molecules are highly branched, and the high content of hydroxyl groups leads to very good solubility in aqueous media. Polysucroses behave as an ideal neutral sphere and displays excellent biocompatibility. Polysucrose does not contain any ionized groups, so it compatible under physiological conditions. Polysucrose is more sensitive to acid than dextran so that care must be taken when working at acid pH.
Properties of the polysucroses include:
Readily soluble in water and electrolyte solution
Clear and stable solutions
No charged groups - neutral polymer
Excellent stability - can be autoclaved
From renewable resources and is readily degraded in ecological systems
All batches are checked for molecular weight, degree of substitution and loss on drying. TdB Labs produce Polysucrose from 20 kDa to 1000 kDa. Polysucrose is provided as a dry powder and is extremely hydrophilic.
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Structure Polysucrose is a polymer synthesised by cross-linking sucrose with epichlorohydrin. Polysucrose has a more spherical structure and is less flexible compared to dextran.
Storage and stability
Polysucrose is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.
Solubility Polysucrose dissolves readily in water.
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