Dextran sulfate 8 is a low molecular weight dextran derivative produced by sulfation of selected dextran fractions. TdB Labs produce both low sulfated and hight sulfated dextran sulfate 8, where 8 represents a molecular weigh of 8000 Da. The full name is Dextran sulfate (sulphate) sodium salt 8kDa.
Dextran sulfate 8 from TdB Labs is made by a novel and unique know-how procedure, which gives a white powder with low absorbance and excellent stability. The product does not contain pyridine and is therefore non-toxic.
Dextran sulfate 8 is supplied as the sodium salt and is stabilised by addition of very small quantities of phosphate salts. The molecular weight for each batch is measured thoroughly and declared as Mw and Mn in the Certificate of Analysis (CoA) provided to the customer for each batch. Each batch-specific molecular weight declared refers to values obtained after product sulfation. The CoA supplied to the customer declares also other crucial quality parameters of the current batch of the product. The molecular weight range, sulfur content, moisture etc. are carefully controlled, documented and declared to the customer.
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Structure Dextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of sidechains linked to the 3-carbon of glucose. Dextran sulfate 8 is a sulfated derivative of selected dextran fraction. The sulfate content of our low sulfated dextran sulfate 8 kDa lies between 8 to 13 %, the degree of sulfatation of our high sulfated dextran sulfate 8 kDa is between 16 to 20 %.
Storage and Storage and stability
Dextran sulfate 8 is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature
Dextran sulfate 8 is readily soluble in water.
Dextran sulfate 8 or low molecular weight dextran sulfate sodium salt has a wide range of applications areas and properties.
Dextran sulfate 8 is a common additive in cell culture media where it is often used as an anti-coagulant.
Used in cosmetics for anti-inflammation properties and osmotic retention of water
Separation of microorganisms and macromolecules
Adjuvant in vaccines
Studies of perm selectivity of membranes
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