Antonia Red™ is a red-shifted dye with an absorbance maximum at 583 and an emission wavelength of 602 nm. All batches are carefully controlled for molecular weight, appearance, solubility, degree of substitution, fluorescence and free dye. TdB Labs produce Antonia Red-dextran from 4 kDa to 150 kDa. Antonia Red-dextrans are supplied as a purple powder.
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Antonia Red™-dextran is synthesised from well-characterised dextran fractions derived from Leuconostoc mesenteroides. The dextran fractions are then labelled with Antonia Red. The degree of substitution lies between 0.001-0.01.
Antonia Red™-dextran has an absorbance maximum at 583 nm and an emission wavelength of 602 nm in borate buffer at pH 9.0.
Storage and stability
Antonia Red™-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature
Antonia Red™-dextran dissolves readily in water.
Antonia Red™-dextran is mainly used for studying permeability and microcirculation. It can also be used as a molecular size marker, for studies of drug delivery and more. Antonia Red shows bright fluorescence, has good photo- and chemical stability and is non-pH dependent. Read more about applications here.
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Gustafsson, S. et al. Blood-brain barrier integrity in a mouse model of Alzheimer’s disease with or without acute 3D6 immunotherapy. Neuropharmacology143, 1–9 (2018).
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