Antonia Red™ Dextrans

Antonia Red™ Dextrans

Antonia Red™ is a red-shifted dye with an absorbance maximum at 583 and an emission wavelength of 602 nm. All batches are carefully controlled for molecular weight, appearance, solubility, degree of substitution, fluorescence and free dye. TdB Labs produce Antonia Red-dextran from 4 kDa to 150 kDa. Antonia Red-dextrans are supplied as a purple powder.

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Structure
Antonia Red™-dextran are synthesised from well-characterised dextran fractions derived from Leuconostoc mesenteroides. The dextran fractions are then labelled with Antonia Red. The degree of substitution lies between 0.001-0.01.

Spectral data
Antonia Red™-dextran has an absorbance maximum at 583 nm and an emission wavelength of 602 nm in borate buffer at pH 9.0.

Storage and stability
Antonia Red™ dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature

Solubility
Antonia Red™-dextran dissolves readily in water.

Application
Antonia Red™-dextran is mainly used for studying permeability and microcirculation. It can also be used as a molecular size marker, for studies of drug delivery and more. Antonia Red shows bright fluorescence, has good photo- and chemical stability and is non-pH dependent. Read more about applications here.

References

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Gustafsson, S. et al. Blood-brain barrier integrity in a mouse model of Alzheimer’s disease with or without acute 3D6 immunotherapy. Neuropharmacology 143, 1–9 (2018).

How to order

Visit our webshop to see the molecular weights and pack sizes available. Please send an e-mail to order@tdblabs.se if you would like to receive a quote, place a bulk order or if you wish to place your order manually.

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