FITC-TRITC-dextran 500

CAS Number: N/A
Alternative Name: FTD

FITC-TRIC-dextran (FTD) is a dextran derivative that is labelled with two fluorophores, FITC and TRITC (see Fig 1) and it is currently produced at a molecular weight of 500 kDa.

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Structure and physical properties
Structurally, each of the fluorophores (FITC and TRITC) are bound to dextran through thiourethane linkages (Fig 1). The degree of substitution (DS) lies in the range of 0.001 to 0.020 mol of dye per mole of glucose units for each of the fluorophores. The molar ratio of FITC/TRITC bound to dextran can vary between 1:1 and 2:1 and it is assessed spectrophotometrically at a neutral pH.

Storage and stability
FTD500 should be stored in a well-sealed container in the dark, at room temperature.

Solubility
FTD500 is delivered as a pink powder, that is highly soluble in water and DMSO. However, it is incompatible with strong oxidizing agents.

Application
FTD500 is suitable for applications requiring accurate detection and monitoring of pH in living cells or tissues, where it can operate at a wide range of pH spanning from 3.5 to 8.0.

References

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How to order

Visit our webshop to see the molecular weights and pack sizes available. Please send an e-mail to order@tdblabs.se if you would like to receive a quote, place a bulk order or if you wish to place your order manually.