FITC-Q-dextran

FITC -Q-dextran

FITC-Q-dextran is a positively charged polysaccharide labelled with FITC. Unlike DEAE-dextrans, Q-dextrans will be charged over a wide range of pH (pH 4-10). These products will have a much stronger net charge than corresponding DEAE-dextrans and thus give enhanced responses in systems where this effect is important. All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. TdB Labs produces a FITC-Q-dextran with a molecular weight of 10 kDa. FITC-Q-dextran is supplied as a yellow powder.

Can’t find what you are looking for? We can always produce a customised product for you. Read more here.

Structure
Dextran is a branched polysaccharide elaborated by the bacteria Leuconostoc mesenteroides B512F. Unlike the cationic Diethylaminoethyl (DEAE)-dextran, Q-dextran carries only quaternary amine groups. The nitrogen content is approximately 2% (by elemental analysis) which corresponds to approximately one quaternary ammonium group for every four glucose units.

Spectral data

Storage and stability
FITC-Q-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.

Solubility
FITC-Q-dextran dissolves readily in water.

Application
FITC-dextran is mainly used for studying permeability and microcirculation. The Q-groups will impart an overall positive charge to the molecule, which may be valuable in gaining information on the permeability characteristics of cell membranes and tissues. FITC-Q-dextran have a much stronger net charge than corresponding DEAE-dextran. Read more about applications here.

References

Have you cited this product in a publication? Let us know so we can reference it.

Technical documents

How to order

Visit our webshop to see the molecular weights and pack sizes available. Please send an e-mail to order@tdblabs.se if you would like to receive a quote, place a bulk order or if you wish to place your order manually.

In need of an expert on
dextran derivatives?

Let TdB Labs’ products and services help you achieve your research goals.

 

BonaPostualata20

 

What do you think about this website?